Fatemeh Momen Heravi, DDS, MPH, PhD

Professor
Department of Orofacial Sciences; Chair, Division of Periodontics

Dr. Flora (Fatemeh) Momen-Heravi is an internationally recognized clinician-scientist and periodontist whose work bridges mucosal immunology, periodontology, cancer biology, and precision medicine. As the R. Earl Robinson Distinguished Professor of Periodontology and Division Chief of Periodontology at Department of Orofacial Sciences, she leads pioneering research into the immune system’s interactions with the tumor microenvironment and inflammatory diseases, including oral and periodontal disease.

Dr. Momen-Heravi’s multidisciplinary research program integrates experimental, computational, and translational approaches to uncover disease mechanisms, identify biomarkers, and develop targeted therapeutics. Her laboratory is advancing knowledge in cancer immunology, extracellular vesicles, inflammatory signaling, and precision therapeutics, with ongoing projects in exosome biology, host-pathogen interactions, and genome engineering using CRISPR/Cas.

With a strong background in translational science, Dr. Momen-Heravi previously founded and led the Head and Neck Cancer Research Group at Columbia University Medical Center before joining UCSF in 2024. She has trained extensively at Harvard Medical School, UMASS Medical School, and Brigham and Women’s Hospital and has authored over 120 peer-reviewed publications. Her research is supported by multiple NIH and foundation grants, including R35, R01, and U01 awards, and she has been honored with numerous prestigious awards, such as the AACR-The Mark Foundation ‘Science of the Patient’ Award, the NIH Maximizing Investigators Research Award, and the IADR Young Investigator Award.

Dr. Momen-Heravi is passionate about mentorship, scientific innovation, and bridging health disparities in cancer and periodontal disease. Her lab welcomes motivated postdoctoral fellows, PhD candidates, and dental students interested in cutting-edge research at the intersection of oral and systemic health, immunology, and precision medicine. Dr. Momen-Heravi takes pride in providing full scope of periodontal and implants surgery to patients and manage medically compromised patients and patients with history of cancer.

Publications: 

Amplification of MYC and Its Enhancer Correlates With Genetic Ancestry in Lung Squamous Cell Carcinoma.

JCO precision oncology

Jain S, Bai X, Mallick S, Kinghorn B, May B, Yao AG, Allen-Gipson D, Zhang X, Henick BS, Momen-Heravi F, Carrot-Zhang J, Taylor AM

Modeling Epithelial Homeostasis and Perturbation in Three-Dimensional Human Esophageal Organoids.

Biomolecules

Shimonosono M, Morimoto M, Hirose W, Tomita Y, Matsuura N, Flashner S, Ebadi MS, Okayasu EH, Lee CY, Britton WR, Martin C, Wuertz BR, Parikh AS, Sachdeva UM, Ondrey FG, Atigadda VR, Elmets CA, Abrams JA, Muir AB, Klein-Szanto AJ, Weinberg KI, Momen-Heravi F, Nakagawa H

Artificial intelligence-based epigenomic, transcriptomic and histologic signatures of tobacco use in oral squamous cell carcinoma.

NPJ precision oncology

Viet CT, Asam KR, Yu G, Dyer EC, Kochanny S, Thomas CM, Callahan NF, Morlandt AB, Cheng AC, Patel AA, Roden DF, Young S, Melville J, Shum J, Walker PC, Nguyen KK, Kidd SN, Lee SC, Folk GS, Viet DT, Grandhi A, Deisch J, Ye Y, Momen-Heravi F, Pearson AT, Aouizerat BE

Modeling epithelial homeostasis and perturbation in three-dimensional human esophageal organoids.

bioRxiv : the preprint server for biology

Shimonosono M, Morimoto M, Hirose W, Tomita Y, Matsuura N, Flashner S, Ebadi MS, Okayasu EH, Lee CY, Britton WR, Martin C, Wuertz BR, Parikh AS, Sachdeva UM, Ondrey FG, Atigadda VR, Elmets CA, Abrams JA, Muir AB, Klein-Szanto AJ, Weinberg KI, Momen-Heravi F, Nakagawa H

Racial and ethnic disparities in basal cell carcinoma treated by Mohs micrographic surgery: the Columbia experience.

Archives of dermatological research

Donelian A, Liu Z, Trager MH, Momen-Heravi F, Samie FH

Small extracellular vesicles (sEVs)-based gene delivery platform for cell-specific CRISPR/Cas9 genome editing.

Theranostics

Dubey S, Chen Z, Jiang YJ, Talis A, Molotkov A, Ali A, Mintz A, Momen-Heravi F

HSP90 inhibition suppresses tumor glycolytic flux to potentiate the therapeutic efficacy of radiotherapy for head and neck cancer.

Science advances

Chen F, Tang C, Yang F, Ekpenyong A, Qin R, Xie J, Momen-Heravi F, Saba NF, Teng Y

Efficacy of Horizontal Alveolar Ridge Expansion Through the Alveolar Ridge Split Procedure: A Systematic Review and Meta-Analysis.

The International journal of oral & maxillofacial implants

Al Haydar B, Kang P, Momen-Heravi F

Molecular Subtypes of Head and Neck Cancer in Patients of African Ancestry.

Clinical cancer research : an official journal of the American Association for Cancer Research

Mezghani N, Yao A, Vasilyeva D, Kaplan N, Shackelford A, Yoon A, Phillipone E, Dubey S, Schwartz GK, Taylor AM, Momen-Heravi F

Patient-derived three-dimensional culture techniques model tumor heterogeneity in head and neck cancer.

Oral oncology

Parikh AS, Yu VX, Flashner S, Okolo OB, Lu C, Henick BS, Momen-Heravi F, Puram SV, Teknos T, Pan Q, Nakagawa H

Efficacy of Er,Cr:YSGG Laser Application in Nonsurgical Treatment of Peri-implantitis: A Human Randomized Controlled Trial.

The International journal of periodontics & restorative dentistry

Kang P, Sanz-Miralles E, Li J, Linden E, Momen-Heravi F

Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids.

Journal of visualized experiments : JoVE

Flashner S, Martin C, Matsuura N, Shimonosono M, Tomita Y, Morimoto M, Okolo O, Yu VX, Parikh AS, Klein-Szanto AJP, Yan K, Gabre JT, Lu C, Momen-Heravi F, Rustgi AK, Nakagawa H

SP140 inhibits STAT1 signaling, induces IFN-? in tumor-associated macrophages, and is a predictive biomarker of immunotherapy response.

Journal for immunotherapy of cancer

Tanagala KKK, Morin-Baxter J, Carvajal R, Cheema M, Dubey S, Nakagawa H, Yoon A, Cheng YL, Taylor A, Nickerson J, Mintz A, Momen-Heravi F

Evaluating the Combined Anticancer Response of Checkpoint Inhibitor Immunotherapy and FAP-Targeted Molecular Radiotherapy in Murine Models of Melanoma and Lung Cancer.

Cancers

Capaccione KM, Doubrovin M, Braumuller B, Leibowitz D, Bhatt N, Momen-Heravi F, Molotkov A, Kissner M, Goldner K, Soffing M, Ali A, Mintz A

Decoding the role of macrophages in periodontitis and type 2 diabetes using single-cell RNA-sequencing.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Agrafioti P, Morin-Baxter J, Tanagala KKK, Dubey S, Sims P, Lalla E, Momen-Heravi F

Alcohol Metabolism Enriches Squamous Cell Carcinoma Cancer Stem Cells That Survive Oxidative Stress via Autophagy.

Biomolecules

Shimonosono M, Tanaka K, Flashner S, Takada S, Matsuura N, Tomita Y, Sachdeva UM, Noguchi E, Sangwan V, Ferri L, Momen-Heravi F, Yoon AJ, Klein-Szanto AJ, Diehl JA, Nakagawa H

Differential DNA methylation and mRNA transcription in gingival tissues in periodontal health and disease.

Journal of clinical periodontology

Kim H, Momen-Heravi F, Chen S, Hoffmann P, Kebschull M, Papapanou PN

Protective effect of LNA-anti-miR-132 therapy on liver fibrosis in mice.

Molecular therapy. Nucleic acids

Momen-Heravi F, Catalano D, Talis A, Szabo G, Bala S

Down-regulation of the tumor suppressor miR-34a contributes to head and neck cancer by up-regulating the MET oncogene and modulating tumor immune evasion.

Journal of experimental & clinical cancer research : CR

Wu X, Cheng YL, Matthen M, Yoon A, Schwartz GK, Bala S, Taylor AM, Momen-Heravi F

MicroRNA-Based Cancer Mortality Risk Scoring System and hTERT Expression in Early-Stage Oral Squamous Cell Carcinoma.

Journal of oncology

Yoon AJ, Santella RM, Wang S, Kutler DI, Carvajal RD, Philipone E, Wang T, Peters SM, Stewart CR, Momen-Heravi F, Troob S, Levin M, AkhavanAghdam Z, Shackelford AJ, Canterbury CR, Shimonosono M, Hernandez BY, McDowell BD, Nakagawa H

Cell Type-Specific Decomposition of Gingival Tissue Transcriptomes.

Journal of dental research

Momen-Heravi F, Friedman RA, Albeshri S, Sawle A, Kebschull M, Kuhn A, Papapanou PN

Extracellular Vesicles as Biomarkers in Cancer Immunotherapy.

Cancers

Mathew M, Zade M, Mezghani N, Patel R, Wang Y, Momen-Heravi F

Disruption of Monocyte and Macrophage Homeostasis in Periodontitis.

Frontiers in immunology

Almubarak A, Tanagala KKK, Papapanou PN, Lalla E, Momen-Heravi F

MicroRNA-based risk scoring system to identify early-stage oral squamous cell carcinoma patients at high-risk for cancer-specific mortality.

Head & neck

Yoon AJ, Wang S, Kutler DI, Carvajal RD, Philipone E, Wang T, Peters SM, LaRoche D, Hernandez BY, McDowell BD, Stewart CR, Momen-Heravi F, Santella RM

The clinical and radiographic outcomes of Schneiderian membrane perforation without repair in sinus elevation surgery.

Clinical implant dentistry and related research

Park WB, Han JY, Kang P, Momen-Heravi F

Isolation of Extracellular Vesicles for Cancer Diagnosis and Functional Studies.

Methods in molecular biology (Clifton, N.J.)

Brenner AW, Su GH, Momen-Heravi F

Extracellular vesicles and their nucleic acids for biomarker discovery.

Pharmacology & therapeutics

Momen-Heravi F, Getting SJ, Moschos SA

miRNA regulation of innate immunity.

Journal of leukocyte biology

Momen-Heravi F, Bala S

Extracellular vesicles from mice with alcoholic liver disease carry a distinct protein cargo and induce macrophage activation through heat shock protein 90.

Hepatology (Baltimore, Md.)

Saha B, Momen-Heravi F, Furi I, Kodys K, Catalano D, Gangopadhyay A, Haraszti R, Satishchandran A, Iracheta-Vellve A, Adejumo A, Shaffer SA, Szabo G

Emerging role of non-coding RNA in oral cancer.

Cellular signalling

Momen-Heravi F, Bala S

Tumor expression of calcium sensing receptor and colorectal cancer survival: Results from the nurses' health study and health professionals follow-up study.

International journal of cancer

Momen-Heravi F, Masugi Y, Qian ZR, Nishihara R, Liu L, Smith-Warner SA, Keum N, Zhang L, Tchrakian N, Nowak JA, Yang W, Ma Y, Bowden M, da Silva A, Wang M, Fuchs CS, Meyerhardt JA, Ng K, Wu K, Giovannucci E, Ogino S, Zhang X

Calcium intake and risk of colorectal cancer according to expression status of calcium-sensing receptor (CASR).

Gut

Yang W, Liu L, Masugi Y, Qian ZR, Nishihara R, Keum N, Wu K, Smith-Warner S, Ma Y, Nowak JA, Momen-Heravi F, Zhang L, Bowden M, Morikawa T, Silva AD, Wang M, Chan AT, Fuchs CS, Meyerhardt JA, Ng K, Giovannucci E, Ogino S, Zhang X

Extracellular vesicles in liver disease and potential as biomarkers and therapeutic targets.

Nature reviews. Gastroenterology & hepatology

Szabo G, Momen-Heravi F

Extracellular vesicle isolation: present and future.

Annals of translational medicine

Furi I, Momen-Heravi F, Szabo G

Assessment of arterial stiffness in periodontitis using a novel pulse wave imaging methodology.

Journal of clinical periodontology

Sanz-Miralles EC, Li R, Momen-Heravi F, Mendieta C, Konofagou EE, Papapanou PN

Isolation of Extracellular Vesicles by Ultracentrifugation.

Methods in molecular biology (Clifton, N.J.)

Momen-Heravi F

Periodontal disease, tooth loss and colorectal cancer risk: Results from the Nurses' Health Study.

International journal of cancer

Momen-Heravi F, Babic A, Tworoger SS, Zhang L, Wu K, Smith-Warner SA, Ogino S, Chan AT, Meyerhardt J, Giovannucci E, Fuchs C, Cho E, Michaud DS, Stampfer MJ, Yu YH, Kim D, Zhang X

Management of cannabis-induced periodontitis via resective surgical therapy: A clinical report.

Journal of the American Dental Association (1939)

Momen-Heravi F, Kang P

Facial Anthropometric Norms of the Young Iranian Population.

Journal of maxillofacial and oral surgery

Bayat M, Shariati M, Rajaeirad F, Yekaninejad MS, Momen-Heravi F, Davoudmanesh Z

Bone Reconstruction following Application of Bone Matrix Gelatin to Alveolar Defects: A Randomized Clinical Trial.

International journal of organ transplantation medicine

Bayat M, Momen Heravi F, Mahmoudi M, Bahrami N

Increased number of circulating exosomes and their microRNA cargos are potential novel biomarkers in alcoholic hepatitis.

Journal of translational medicine

Momen-Heravi F, Saha B, Kodys K, Catalano D, Satishchandran A, Szabo G

Selection bias.

Journal of the American Dental Association (1939)

Momen-Heravi F

Biodistribution and function of extracellular miRNA-155 in mice.

Scientific reports

Bala S, Csak T, Momen-Heravi F, Lippai D, Kodys K, Catalano D, Satishchandran A, Ambros V, Szabo G

In vitro and ex vivo antimicrobial efficacy of nano-MgO in the elimination of endodontic pathogens.

Clinical oral investigations

Monzavi A, Eshraghi S, Hashemian R, Momen-Heravi F

Genomewide Study of Salivary MicroRNAs for Detection of Oral Cancer.

Journal of dental research

Momen-Heravi F, Trachtenberg AJ, Kuo WP, Cheng YS

Exosome-mediated delivery of functionally active miRNA-155 inhibitor to macrophages.

Nanomedicine : nanotechnology, biology, and medicine

Momen-Heravi F, Bala S, Bukong T, Szabo G

Emerging technologies in extracellular vesicle-based molecular diagnostics.

Expert review of molecular diagnostics

Jia S, Zocco D, Samuels ML, Chou MF, Chammas R, Skog J, Zarovni N, Momen-Heravi F, Kuo WP

Current methods for the isolation of extracellular vesicles.

Biological chemistry

Momen-Heravi F, Balaj L, Alian S, Mantel PY, Halleck AE, Trachtenberg AJ, Soria CE, Oquin S, Bonebreak CM, Saracoglu E, Skog J, Kuo WP

A comparison of viscoelastic properties of three root canal sealers.

Journal of dentistry (Tehran, Iran)

Khedmat S, Momen-Heravi F, Pishvaei M

Alternative methods for characterization of extracellular vesicles.

Frontiers in physiology

Momen-Heravi F, Balaj L, Alian S, Tigges J, Toxavidis V, Ericsson M, Distel RJ, Ivanov AR, Skog J, Kuo WP

Impact of biofluid viscosity on size and sedimentation efficiency of the isolated microvesicles.

Frontiers in physiology

Momen-Heravi F, Balaj L, Alian S, Trachtenberg AJ, Hochberg FH, Skog J, Kuo WP

Ultrasound-guided simultaneous irrigation and drainage of facial abscess.

The Journal of craniofacial surgery

Abbasi M, Bayat M, Beshkar M, Momen-Heravi F

Comparison of aloe vera mouthwash with triamcinolone acetonide 0.1% on oral lichen planus: a randomized double-blinded clinical trial.

The American journal of the medical sciences

Mansourian A, Momen-Heravi F, Saheb-Jamee M, Esfehani M, Khalilzadeh O, Momen-Beitollahi J

Molecular imaging for stem cell transplantation in neuroregenerative medicine.

Neuro-degenerative diseases

Sandu N, Momen-Heravi F, Sadr-Eshkevari P, Schaller B

Informed consent: dissimilar linguistic barriers in different societies.

Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons

Momen-Heravi F, Khalilzadeh O, Dorriz H

Transverse displacement and angulation of the proximal segment after mandibular setback by means of bilateral intraoral vertico-sagittal ramus osteotomy.

Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons

Bayat M, Badri A, Momen-Heravi F, Garajei A, Asgarian A

Genetic susceptibility to Graves' ophthalmopathy: The role of polymorphisms in anti-inflammatory cytokine genes.

Ophthalmic genetics

Khalilzadeh O, Anvari M, Esteghamati A, Momen-Heravi F, Rashidi A, Amiri HM, Tahvildari M, Mahmoudi M, Amirzargar A

Trigeminal cardiac reflex: another all-or-none law?

Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons

Bohluli B, Schaller B, Sadr-Eshkevari P, Momen-Heravi F

Assessment of salivary and serum antioxidant status in patients with recurrent aphthous stomatitis.

Medicina oral, patologia oral y cirugia bucal

Momen-Beitollahi J, Mansourian A, Momen-Heravi F, Amanlou M, Obradov S, Sahebjamee M

Sandwich bone graft covered with buccal fat pad in severely atrophied edentulous maxilla: a clinical report.

The Journal of oral implantology

Khojasteh A, Mohajerani H, Momen-Heravi F, Kazemi M, Alikhasi M

Three-dimensional accuracy of implant and abutment level impression techniques: effect on marginal discrepancy.

The Journal of oral implantology

Alikhasi M, Siadat H, Monzavi A, Momen-Heravi F

Comparison of colchicine versus prednisolone in recurrent aphthous stomatitis: A double-blind randomized clinical trial.

Clinical and investigative medicine. Medecine clinique et experimentale

Pakfetrat A, Mansourian A, Momen-Heravi F, Delavarian Z, Momen-Beitollahi J, Khalilzadeh O, Basir-Shabestari S

The interleukin-1 family gene polymorphisms and Graves' disease.

Annales d'endocrinologie

Khalilzadeh O, Anvari M, Esteghamati A, Momen-Heravi F, Mahmoudi M, Rashidi A, Amiri HM, Ranjbar M, Tabataba-Vakili S, Amirzargar A

Graves' disease and gene polymorphism of TNF-α, IL-2, IL-6, IL-12, and IFN-γ.

Endocrine

Anvari M, Khalilzadeh O, Esteghamati A, Momen-Heravi F, Mahmoudi M, Esfahani SA, Rashidi A, Amirzargar A

Comparison of conchal cartilage graft with nasal septal cartilage graft for reconstruction of orbital floor blowout fractures.

The British journal of oral & maxillofacial surgery

Bayat M, Momen-Heravi F, Khalilzadeh O, Mirhosseni Z, Sadeghi-Tari A

A comparison of bone reconstruction following application of bone matrix gelatin and autogenous bone grafts to alveolar defects: an animal study.

Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery

Bayat M, Momen-Heravi F, Marjani M, Motahhary P

Gene polymorphisms of interleukin-4, interleukin-10 and transforming growth factor-beta in Graves' disease.

Clinical and experimental medicine

Khalilzadeh O, Anvari M, Momen-Heravi F, Esteghamati A, Rashidi A, Mahmoudi M, Nikbin B, Amirzargar A

The efficacy of a paste containing Myrtus communis (Myrtle) in the management of recurrent aphthous stomatitis: a randomized controlled trial.

Clinical oral investigations

Babaee N, Mansourian A, Momen-Heravi F, Moghadamnia A, Momen-Beitollahi J